Search on: UNCOUPLING AGENTS 
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Descriptor English:   Uncoupling Agents 
Descriptor Spanish:   Desacopladores 
Descriptor Portuguese:   Desacopladores 
Tree Number:   D27.505.519.389.936
Definition English:   Chemical agents that uncouple oxidation from phosphorylation in the metabolic cycle so that ATP synthesis does not occur. Included here are those IONOPHORES that disrupt electron transfer by short-circuiting the proton gradient across mitochondrial membranes. 
Indexing Annotation English:   enzyme inhib
See Related English:   Ionophores
 
History Note English:   72(69) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DU diagnostic use
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   14874 
Unique Identifier:   D014475 

Occurrence in VHL:
 

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